$3 Wound Healing Device Saving Lives in Haiti

A student at MIT has created a device that helps people heal after severe wounds that costs a fraction of what commercial options cost. The device is a portable version of the negative-pressure devices that accelerates wound healing and reduces the frequency that bandages need to be changed. Commercially available devices cost about $100 and require a lot more energy than the MIT designed $3 device.

Negative-pressure devices, which act like a vacuum over the bandaged wound, have become a central part of wound therapy in the United States over the last decade. They speed healing up to threefold, depending on the type of wound, and in some cases eliminate the need for plastic surgery or skin grafts. A number of commercial versions are available in the U.S. and are used to treat burns and chronic wounds such as bed sores or diabetic foot ulcers. While scientists don’t exactly know why this treatment accelerates the healing process, it likely helps by removing some of the fluid and bacteria that accumulates at the injury site and by increasing blood flow to the wound. The pressure itself may also help healing by bringing together the edges of the wound and delivering mechanical pressure, which has been shown to spur cell growth, says Dennis Orgill, a surgeon at Brigham and Women’s who was not involved in the project.

Existing devices are often heavy, about five to 10 pounds, and require an energy source to create the vacuum, making them difficult to apply in disaster settings. Texas-based KCI, the leading maker of negative-pressure machines, has a portable version that’s battery powered, but it costs approximately $100 per day to rent. A number of companies are working on even more portable versions, say Orgill.

Keep reading at Technology Review.

Vancouver Safe Injection Site Survives

Vancouver’s Insite is the first safe injection site in North America. The project has been shown to reduce public drug use, needle sharing, littering, and increase addiction treatment. The Canadian government has been trying to shut it down recently, but in January, Insite won a court battle that recognized them as providing an “essential medical service.”

The B.C. Court of Appeal has dismissed a federal government appeal, which means InSite, the Vancouver supervised safe-injection site that was the first of its kind in Canada, will remain open.

The federal government is expected to appeal Friday’s split 2-1 ruling to the Supreme Court of Canada.

Vancouver Mayor Gregor Robertson reacted by saying he strongly supports the ruling and the continued operation of InSite to improve the lives of drug addicts.

“With this second consecutive decision in favour of InSite, I hope the federal government will drop its legal efforts so that we can go back to focusing on InSite for what it is — a harm reduction facility that saves lives and improves health outcomes for those living with addictions,” the mayor said in a statement.

Read the whole article at the Vancouver Sun

Virus Shown To Treat Prostate Cancer

A team of researchers in Alberta have successfully tested a new way to treat prostate cancer with a virus. Viruses, which target specific cells, are injected into the body and seek out the mutations in cancer cells. The virus then replicates and causes the cancer cell to burst, sending thousands of viral particles into the surrounding tumour.

The six men in the study had the virus injected directly into their tumours three weeks before they had surgery to remove the prostate gland as part of standard treatment. The tumour cells are targeted by viruses in the experimental treatment, says Dr. Don Morris of the Tom Baker Cancer Centre in Calgary.

Signs of cancer-cell death were found in the removed prostate tumour, while the normal parts of the prostate showed minimal toxicity and no viral replication, Morris said.

Although this doesn’t represent a cure for cancer (tumours were very rarely completely eliminated), it may lead to cancer becoming a much more treatable illness.

Read more at Cbc.ca.

Using Trees To Provide Clean Water.

It turns out that trees can do more than just provide power! The Moringa tree, which grows in Africa, India, South East Asia, and Central and South America, is drought resistant and capable of producing cooking and lighting oil, soil fertilizer, and nutritious food.  In addition, it has be recently publicized that the seeds can reduce the bacteria count in previously untreated water by 90.00 – 99.99%! Although the process can be quite involved, it still has the potential to allow people to have unrestrained access to clean water.

Read a bit more at Gizmag.com, or read the entire article as published in Current Protocols in Microbiology.

Cuff the Heart

A new cuff can help save heart attack victims by limiting blood flow.

Ischemic preconditioning involves using the device to interrupt blood flow in the arm, off and on over a period of 35 to 40 minutes: the cuff is inflated for five minutes, then deflated for five minutes, with the procedure being repeated consecutively four times.

Once at the hospital, the patient receives routine heart attack treatment, including cardiac angioplasty. Preconditioning using the cuff may still be going on throughout this procedure, which uses a tiny inflatable balloon to open up narrowed or blocked blood vessels to the heart.

Researchers, whose paper appears in Friday’s issue of The Lancet, found that those heart attack patients randomly assigned to have preconditioning had an overall reduction in heart muscle damage of 30 per cent, compared to those not treated with the cuff.

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