Health – Things Are Good

Stay Young By Enjoying Art

Who doesn’t like art? If you find yourself answering “me” to that question then perhaps you should check out different galleries. Recent research has shown that people who regularly engage with art and feel something about it tend to age slower. Even engaging with art all east once a month show a 3% decrease in aging speed. Neat!

Stay young, enjoy art, live life.

“These results demonstrate the health impact of the arts at a biological level,” said Daisy Fancourt, the study’s lead author and the head of University College London’s social biobehavioral research group, told The Guardian. “They provide evidence for arts and cultural engagement to be recognized as a health-promoting behavior in a similar way to exercise.”

The study was conducted among 3,356 adults between 2010 and 2012, and included survey data and blood tests. Individuals’ rate of aging was assessed according to epigenetic clocks, which are analytic methods that track age-related changes to DNA and can be used to estimate biological age, which may differ from a person’s chronological age.

A Human on a Bicycle: Incredibly Efficient

Graph showing how efficient a human travelling on a bicycle is, more efficient than a horse

With the recent Israeli and American attack on Iran the price of oil has shot up and shows no signs of going back down. This seems like a good time to remind people that a bicycle is the most efficient form of human-powered transportation. Indeed, the graph above is an update to a popular graph showing efficient transportation, but grouped into the animal kingdoms. Save gas, save money, and get fit by riding a bike this summer.

Travel involves two main expenditures of energy: fighting gravity and propelling yourself forward. Most terrestrial animals must expend energy first to stand up, then to take each step forward. (Longer-legged land creatures tend to be more efficient because they get more distance out of each step, which explains why mice are so inefficient.) Flying animals, though, can move forward cheaply by gliding through the air, carried more by currents than by their own power. Swimming animals can similarly glide through water while letting their natural buoyancy minimize the need to fight gravity.

Successful Treatment for Huntington’s Disease

nurses walking in a hallway

Huntington’s disease is a neurological disease that combines dementia and motor neurone issues, making for a very unpleasant experience. Historically, people suffering from Huntington’s disease had low prospects for living their lives as they normally did and a shorter lifespan. A UK team has developed a very interesting solution to treat Huntington’s disease by injecting modified viruses directly into the brain, the really cool thing is that these little viruses then block the ability of Huntington’s disease to spread. It’s a novel and very 21st century approach and good news not only for people who may get Huntington’s but also for related neurological diseases.

It starts with a safe virus that has been altered to contain a specially designed sequence of DNA.

This is infused deep into the brain using real-time MRI scanning to guide a microcatheter to two brain regions – the caudate nucleus and the putamen. This takes 12 to 18 hours of neurosurgery.

The virus then acts like a microscopic postman – delivering the new piece of DNA inside brain cells, where it becomes active.

This turns the neurons into a factory for making the therapy to avert their own death.

The cells produce a small fragment of genetic material (called microRNA) that is designed to intercept and disable the instructions (called messenger RNA) being sent from the cells’ DNA for building mutant huntingtin.

This results in lower levels of mutant huntingtin in the brain.

Plant Based Diet Connected to Lower COVID-19 Rates

Covid-19 Transmission graphic

It’s been years that we’ve been living with COVID-19 and it looks like we missed the window to fully eradicate it, which means we need to adapt our lifestyles to ensure that rates of transmission are as low as possible. Of course, the obvious things involve collective action like improving indoor air quality and filtration. As an individual you should consider switching to a plant based diet.

Plant-based and vegetarian groups had a higher intake of vegetables, legumes and nuts, and lower intake of dairy and meat. After adjusting for important confounders, such as body mass index, physical activity and pre-existing medical conditions, the plant-based diet and vegetarian group had 39% (OR=0.61, 95%?CI 0.44 to 0.85; p=0.003) and 39% (OR 0.61, 95%?CI 0.42 to 0.88; p=0.009) lower odds of the incidence of COVID-19 infection, respectively, compared with the omnivorous group. No association was observed between self-reported diets and COVID-19 severity or duration.

Conclusion Plant-based and mainly vegetarian diets were associated with a lower incidence of COVID-19 infection. These dietary patterns may be considered protective against COVID-19 infection. (Study protocol registered in CAAE: 54351421.4.0000.0068.)

mRNA Vaccine Used to Fight Brain Tumour

Brain tumours are scary and very difficult to deal with, current treatments include invasive surgery and/or radiation. The advent of mRNA based vaccines is making a difference in how we can treat various brain cancers and the early results are looking promising. A team just found a way to get the body’s immune system to start to find and address cancer within the brain. While the results are not yet usable the outlook is very promising.

“The demonstration that making an mRNA cancer vaccine in this fashion generates similar and strong responses across mice, pet dogs that have developed cancer spontaneously and human patients with brain cancer is a really important finding, because oftentimes we don’t know how well the preclinical studies in animals are going to translate into similar responses in patients,” said Duane Mitchell, M.D., Ph.D., director of the UF Clinical and Translational Science Institute and the UF Brain Tumor Immunotherapy Program and a co-author of the paper. “And while mRNA vaccines and therapeutics are certainly a hot topic since the COVID pandemic, this is a novel and unique way of delivering the mRNA to generate these really significant and rapid immune responses that we’re seeing across animals and humans.”