HIV Vaccine Showing Promising Results

There are lots of teams trying to create a vaccine for HIV and they are all making valuable progress. HIV is the virus that turns into AIDS which is a life altering diagnosis. Treatments for people with HIV/AIDS have improved greatly over the decades but a vaccine would be the greatest step forward. This new vaccine works at the cellular level to help the body fight off HIV by boosting B cells. Modern science truly is impressive!

The new vaccine works by intervening in a process called B cell maturation. B cells make antibodies. Like many immune cells, B cells have an early “naive” stage before they are ready to make antibodies. B cells start to mature once they get the signal that a pathogen, such as a virus, is trying to attack. B cells see pieces of that pathogen’s molecular structure and start producing antibodies that can bind to that structure and halt infection.

It can take a little while for B cells to find the right “bullseye” on a pathogen. But B cells keep trying. As they mature, B cells tweak their antibody production, refining antibody structures to bind to a pathogen in just the right, vulnerable spots.

Scientists describe B cell development as a training process or bootcamp. In most cases, the body is left with a well-honed B cell army.

HIV is hard to beat because it doesn’t give B cells a chance to develop effective antibodies. The first problem is that HIV disguises itself from the immune system. The virus is wrapped in an ever-shifting cloak of sugar molecules, called glycans. This lets HIV sneak undetected past human cells, which are also covered in glycans.

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Ditching Gas Stoves as Good as Using Drugs for Asthmatics

cooking prep

Having asthma is tough as you may too often feel short of breath, and the solution to many asthma symptoms are prescription drugs. The drugs generally help the body open airways and allow the asthmatic person to breathe normally agin.
It’s been proven that air pollutants increase the stress put on asthmatic individuals and lead to increase asthma rates in the population at large. It’s also known that gas stoves produce a ton of indoor pollution. Put those two things together and now you get a good question: if gas stoves are removed from homes with people with asthma then will their condition improve? The answer is yes!

Indeed, if you get rid of gas stoves then you could see improvements as good as, or exceeding, certain drugs used to treat asthma.

Sehgal said: “We were surprised when we analysed the results and found a very large effect size. The improvements in asthma symptoms following stove change were similar to – or even greater than – those reported in clinical trials of commonly used asthma medications.”

Each person was assessed for four weeks before the gas cooking replacement, and for four weeks afterwards, including scoring their asthma using an internationally recognised scale of zero to six.

The average asthma score improved from 2.6 to 1.5, on a scale where a change of 0.5 is considered to be clinically significant. This included fewer hospital visits and fewer days off school or work for asthma flare-ups. They also found less wheezing, less use of reliver inhalers and fewer people saying that their asthma had woken them during the night.

Air pollution was measured in 44 of the homes. On average, nitrogen dioxide dropped 70%.

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Feeling Overwhelmed? Hit the Floor

Simply lying down on the floor can help calm you down if you’re getting overwhelmed. It sounds too good to be true that simply lying down can work, but the science is there and there’s hundreds of years of observation too. The act of lying down is a yoga pose (probably the easiest yoga pose too) that has been proven to change your physical and mental wellbeing almost instantly.

next time the weight of the world has got you down, let it push you to the floor. Then you can get back up again!

When you’re having a bad day, “floor time is the ultimate grounding technique,” Daryl Appleton, EdD, chief wellness consultant and Fortune 500 executive coach, told Business Insider. Research shows that grounding can reduce inflammation, pain, and stress, which may improve sleep and blood flow.

Compared to when you’re sitting or standing, lying on the floor maximizes your contact with the ground. You may notice your muscles releasing tension with your back and legs supported.

“Getting on the ground outdoors is even better because it allows your nervous system to recalibrate,” Appleton said. Physically connecting with the earth can boost your mood and help you relax and regulate your emotions.

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Stay Young By Enjoying Art

Who doesn’t like art? If you find yourself answering “me” to that question then perhaps you should check out different galleries. Recent research has shown that people who regularly engage with art and feel something about it tend to age slower. Even engaging with art all east once a month show a 3% decrease in aging speed. Neat!

Stay young, enjoy art, live life.

“These results demonstrate the health impact of the arts at a biological level,” said Daisy Fancourt, the study’s lead author and the head of University College London’s social biobehavioral research group, told The Guardian. “They provide evidence for arts and cultural engagement to be recognized as a health-promoting behavior in a similar way to exercise.”

The study was conducted among 3,356 adults between 2010 and 2012, and included survey data and blood tests. Individuals’ rate of aging was assessed according to epigenetic clocks, which are analytic methods that track age-related changes to DNA and can be used to estimate biological age, which may differ from a person’s chronological age.

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Thanks to Fono!

When You Read, Do You Hear Voices?

books

Do you read fiction? Do you find yourself ‘hearing’ the different character voices as you read them (other than audiobooks, naturally). Do you picture the world the story is set in great detail? These are the sort of questions that Reader Bank is all about. It’s a new research project looking into longitudinal behaviours of readers and how it relates to, well, who readers are and how they think. It’s an ambitious project that you can be a part of no matter how much or little you read. Maybe doing their studies will motivate you to read more.

ReaderBank is the world’s most ambitious study of reading, imagination, and wellbeing. Every day, readers around the world lose themselves in novels or poetry, but how and why that happens can be mysterious and unexpected. With ReaderBank, we are aiming to collect a variety of information on what it is to read and imagine. From lively festivals like the Edinburgh International Book Festival and Jaipur Literature Festival, to our own workshops and projects, we collate stories of how literature touches lives across the globe.

ReaderBank explores reading experiences to understand how we imagine, how we think, how we feel, and how we inhabit our everyday worlds.

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