Trichloroethylene Exposure Linked to Parkinson’s

Finding the source of Parkinson’s disease has been a challenge for many researchers and this year we’ve gotten a lot closer to figuring it out. There are multiple ways that one can get the neurodegenerative disease with no one factor being the deciding one. This year alone researchers have found common enzymes in people suffering from Parkinson’s and are in the process of generating faster detection methods for people so treatment can start earlier. Just this week it was revealed that a widely used chemical called trichloroethylene (TCE) has a strong association with people who have Parkinson’s- so much so that it looks like exposure to the chemical can actually cause the disease.

The report, published today in JAMA Neurology, involved examining the medical records of tens of thousands of Marine Corps and Navy veterans who trained at Marine Corps Base Camp Lejeune in North Carolina from 1975 to 1985. Those exposed there to water heavily contaminated with TCE had a 70% higher risk of developing Parkinson’s disease decades later compared with similar veterans who trained elsewhere. The Camp Lejeune contingent also had higher rates of symptoms such as erectile dysfunction and loss of smell that are early harbingers of Parkinson’s, which causes tremors; problems with moving, speaking, and balance; and in many cases dementia. Swallowing difficulties often lead to death from pneumonia.

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Three Day Weekends Rule, Good For Your Health

work and smile

Unions fought hard for a five day work week and now we need to fight for a four day work week. A global study of people who get a three day weekend from their job have better health and are happier. This is quite unsurprising to anyone who has enjoyed a three day weekend. For workplaces that have made shift to a four day work week they have also noticed an uptick in productivity. What are we waiting for?

“When people go on holiday, they’re changing their everyday responsibilities because they’re not locked down to their normal schedule,” Dr Ferguson says.

“In this study, we found that movement patterns changed for the better when on holiday, with increased physical activity and decreased sedentary behaviour observed across the board.

“We also found that people gained an extra 21 minutes of sleep each day they were on holiday, which can have a range of positive effects on our physical and mental health. For example, getting enough sleep can help improve our mood, cognitive function, and productivity. It can also help lower our risk of developing a range of health conditions, such as obesity, diabetes, cardiovascular disease, and depression.

“Interestingly, the size of these changes increased in line with the length of the holiday – so the longer the holiday, the better the health benefits.”

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Diagnosis by Dreams

What you do while dreaming might be a sign of things to come. This isn’t non-scientific phooey, rather this is real science that can help doctors and patients address neurological issues. There’s been an increase in scientists looking at what people do while dreaming to see if they have Parkinson’s or other neurological difficulties, and by examining dream behaviour it might be possible to provide an earlier diagnosis.

In recent years awareness of RBD and an understanding of how it relates to synucleinopathies have grown. Studying this link is giving researchers ideas for early intervention. These advances contribute to a growing appreciation of the so-called prodromal phase of Parkinson’s and other neurodegenerative disorders—when preliminary signs appear, but a definitive diagnosis has not yet been made. Among the early clues for Parkinson’s, “RBD is special,” says Daniela Berg, a neurologist at the University Hospital Schleswig-Holstein in Germany. “It’s the strongest clinical prodromal marker we have.”


Does damage to the brain stem also affect the content of dreams and the actions of dreamers? Sleep researcher Isabelle Arnulf, a professor of neurology at Sorbonne University in Paris, developed a keen interest in the dream-time behaviors of her Parkinson’s patients after noticing an unusual pattern: although these people struggled with movement while awake, their spouses often reported that they had no trouble moving while asleep. One particularly memorable patient, according to Arnulf, had been dreaming of crocodiles in the sleep lab when he lifted a heavy bedside table above his head and loudly shouted, “Crocodile! Crocodile!” to an empty room. When awake, he struggled to lift objects and to speak.

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More Trees Means Less Death

Forest

In the cold of winter you might not be thinking of the nice hot summer days as a negative thing. In the winter when temperatures get really low people suffer from hypothermia or worse, whereas in heat they can suffer from heat stroke or worse. When it comes to the heat there’s a nice and simple solution of planting trees.

In urban environments tree coverage can literally save lives by having a minium of 30% of urban space shaded by trees. Not only will the trees reduce heat in their immediate area they will provide cleaners air and a nicer place to be.

We found substantial variation in UHI death rates across European cities. In 2015, Gothenburg in Sweden recorded no premature UHI deaths, while urban heat was responsible for 32 premature deaths per 100,000 people in the Romanian city Cluj-Napoca.

The cities with the highest UHI death rates were in southern and eastern Europe. Most of these cities generally had low tree coverage and recorded the highest UHI effect.

Just 3.3% of Thessaloniki in Greece is covered by trees, resulting in urban temperatures 2.8? higher than the surrounding area. By contrast, 27% of Gothenburg is covered by trees, delivering an UHI effect of just 0.4?.

Overall, southern European cities will benefit most from increasing their tree cover. Our model estimates that Barcelona could reduce its UHI death rate by 60% by meeting the 30% tree coverage target.

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Judo Falls for the Elderly

When old people fall the results are likely to be far worse than when younger people hit the floor. There’s a long history of technology assistance for elderly individuals who fall from the infamous “I’ve fallen and can’t get up” device to the modern smartwatch with fall detection. As always, the best solution is prevention.

In Quebec an organization has popped up to help teach people how to fall so they don’t injure themselves. Yes, that’s right to prevent falls and help people deal with them is to get them to fall in the first place.

One of the principal lessons is to encourage suppleness and to teach students to not be afraid of falling, says Jean-François Marceau, executive director of Judo Quebec.

As part of the courses, students are taught the basics of how to drop down to — and then get up from — the floor.

“When you go back to that basic thing then you become less afraid of the floor,” said Marceau. “Of course you don’t learn to fall in one lesson and then it’s acquired for life. You have to practise for several weeks … It keeps the reflex on your body and your mind.”

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Thanks to Lindsay!

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